Slicc criteria 2013. 1Universitair Medisch .
Slicc criteria 2013. Welsing1, R. Other consultants’ diagnoses were: UCTD (19. 5%). Objective: The Systemic Lupus International Collaborating Clinics (SLICC) group revised and validated the American College of Rheumatology (ACR) systemic lupus erythematosus (SLE) classification criteria in order to improve clinical relevance, meet stringent methodology requirements, and incorporate new knowledge regarding the immunology of SLE. Methods We The 2019 EULAR/ACR classification criteria were met in 36 patients (26%) and the 2012 SLICC criteria in 33 patients (23. Table A: 2015 ACR/SLICC revised criteria for diagnosis of SLE a b c same as Systemic Lupus International Collaborating Clinics criteria for SLE Feb 12, 2025 · The SLICC criteria require either that a patient satisfy at least 4 of 17 criteria, including at least 1 of the 11 clinical criteria and one of the six immunologic criteria, or that the patient has biopsy-proven nephritis compatible with SLE in the presence of antinuclear antibodies (ANA) or anti-double-stranded DNA (anti-dsDNA) antibodies. Page 19 Table 6 Performance of the SLICC Classification Criteria and the ACR criteria after classifying each of the 690 NIH-PA Author Manuscript patients as either SLE or not SLE based on the principle of “Majority Rules”. Patients with longer disease duration had a larger damage index score. The SLICC criteria for SLE classification requires: 1) Fulfillment of at least four criteria, with at least one clinical criterion AND one immunologic criterion OR 2) Lupus nephritis as the sole clinical criterion in the presence of ANA or anti-dsDNA antibodies. In this classification, biopsy-confirmed lupus nephritis with positive antinuclear or anti-double-stranded DNA antibodies became a stand-alone criterion. 18 May 27, 2025 · Systemic lupus erythematosus (SLE) poses significant diagnostic challenges. Second, no single laboratory test can definitively confirm or exclude the diagnosis. SLICC Criteria for the Diagnosis of Systemic Lupus Erythematosus SLICC Criteria: 4 or more of 17 criteria, including clinical, immunologic, and laboratory features, are required for SLE diagnosis. This study examined large cohorts of subjects with Feb 12, 2025 · The SLICC criteria require either that a patient satisfy at least 4 of 17 criteria, including at least 1 of the 11 clinical criteria and one of the six immunologic criteria, or that the patient has biopsy-proven nephritis compatible with SLE in the presence of antinuclear antibodies (ANA) or anti-double-stranded DNA (anti-dsDNA) antibodies. The Systemic Lupus International Collaborating Clinics (SLICC) developed new SLE criteria to improve the American College of Rheumatology (ACR) criteria but the SLICC criteria have not been evaluated in patients with SCLE. However, when only people who tested positive for antinuclear antibodies (ANA-positive) were included in the analysis, the EULAR/ACR set of criteria detected more false positive lupus cases. SLE Apr 20, 2015 · PDF | On Apr 20, 2015, Iraj Salehi Abari published 2015 ACR/SLICC Revised Criteria for Diagnosis of Systemic Lupus Erythematosus | Find, read and cite all the research you need on ResearchGate As chair of SLICC Dr. Recursive partitioning was used to derive an initial rule that was simplified and refined based on SLICC physician consensus. 11 In the SLICC classification, 11 biopsy-confirmed LN in the presence of antinuclear antibodies (ANA) or anti-double-stranded DNA (anti-dsDNA In 2012, the Systemic Lupus International Collaborating Clinics (SLICC) network presented a set of criteria based on almost 1400 patient scen-arios, including a derivation and a validation of the new criteria as well as of the 1997 ACR classifica-tion. SLICC 2012 criteria performed better than EULAR/ACR 2019 criter … Oct 22, 2024 · Systemic Lupus Erythematosus (SLE) can be diagnosed using the 2012 criteria of the Systemic Lupus International Collaborating Clinics (SLICC) and, more recently, the 2019 criteria of the European League Against Rheumatism/American College of Rheumatology (EULAR/ACR). The SLICC criteria use a combination of clinical and immunologic features to determine whether a patient has SLE. The present study is the first to evaluate the performance of SLICC-12 in an Jul 9, 2013 · The SLE classification criteria proposed by the SLICC in 2012 can be fulfilled in two ways: by biopsy-proven lupus nephritis in the presence of ANAs or anti-DNA antibodies as a 'stand-alone The 2012 Systemic Lupus International Collaborating Clinics (SLICC) classification criteria addressed many of these issues (9). Mar 4, 2025 · Concerning specificity, 1997 ACR criteria demonstrated the highest performance (89. Includes clinical and immunologic criteria. The aim of the study is to compare the performance The present review outlines the clinical characteristics of iSLE after introduction of SLICC criteria and furthermore proposes a definition of iSLE with the aim of discriminating the high- risk group from those with a lower risk. New SLICC classification criteria correlate with disease activity because they capture more manifestations also included in the SLEDAI index. For the eMERGE network*, we are using the SLICC (Systemic Lupus International Collaborating Clinics) Criteria to determine if patients have SLE. Jul 29, 2014 · In uncontrolled settings such as an outpatient rheumatology clinic, the new 2012 Systemic Lupus International Collaborating Clinics (SLICC) criteria are similar to the 1997 American College of Rheumatology criteria to classify patients with systemic lupus erythematosus (SLE). As the precursor of the SLICC group, members of the NATO conference on Prognosis Studies in SLE which took place in 1985 in Toronto, recognized the need for three instruments to better describe the prognosis of SLE including the domains of disease activity, accumulated damage May 2, 2012 · The classification criteria were derived from a set of 702 expert-rated patient scenarios. Despite differences in structure and statistical performance, the EULAR/ACR and SLICC criteria agree on the importance of both immunological and clinical findings, on the high impact of lupus nephritis by histology, and on most clinical items. From this start, the quest for optimal SLE criteria has led to the 1997 ACR update, the 2012 publication of the Systemic Lupus International Collaborating Clinics (SLICC) criteria, and, in 2019, the European League Against Rheumatism (EULAR Data from Aringer M, Costenbader K, Daikh D, et al: 2019 European League Against Rheumatism/American College of Rheumatology Classification Criteria for Systemic Lupus Erythematosus. Oct 1, 2022 · The SLICC criteria also introduced another rule in saying “classify a patient as having SLE if he or she satisfies 4 of the clinical and immunologic criteria used in the SLICC classification criteria, including at least one clinical criterion and one immunologic criterion” [3]. Mar 27, 2024 · In an early SLE cohort the ACR-1997, SLICC-2012 and EULAR/ACR-2019 criteria classify non-overlapping groups of patients: use of all three criteria ensures optimal capture for clinical studies while their modification earlier classification and treatment. May 2, 2012 · The classification criteria were derived from a set of 702 expert-rated patient scenarios. Skills in Rheumatology [Internet]. First, it is characterized by a highly variable combination of autoantibodies and a wide range of possible organ involvement and symptoms. Approximately 50% of patients with subacute cutaneous lupus erythematosus (SCLE) meet criteria for systemic lupus erythematosus (SLE). Patients must have a total of four criteria, with at least one clinical feature and one immunologic feature. Een vergelijking van de classificatie van systemische lupus erythematosus door de 2012 SLICC classificatiecriteria en de 1997 ACR classificatiecriteria. Nov 6, 2019 · The new EULAR/ACR classification criteria for SLE offer improved sensitivity and specificity, as well as more accurately reflect the current tests used to clinically diagnose SLE. 2, 3 Compared with the 1982 and 1997 ACR criteria, SLICC-12 contains additional clinical and immunological items and accepts cases with “renal Dec 22, 2022 · Evaluating performance of the 2019 EULAR/ACR, 2012 SLICC, and 1997 ACR criteria for classifying adult-onset and childhood-onset systemic lupus erythematosus: A systematic review and meta-analysis May 13, 2020 · The overall structure for classification according to the ACR 1982 and 1997, the SLICC 2012, and the EULAR/ACR 2019 classification criteria for SLE The ACR 1997, SLICC 2012 and EULAR/ACR 2019 classification criteria were validated based on adult patients. 9 Mucocutaneous and neuropsychiatric manifestations were added, as were hypocomplementemia and new antiphospholipid antibody tests; and criteria definitions were refined. Mar 1, 2018 · To evaluate the performance in classifying systemic lupus erythematosus by the 2012 Systemic Lupus International Collaborating Clinics criteria (SLICC… Feb 12, 2025 · 2012 SLICC criteria – In 2012, the SLICC proposed classification criteria that were developed to address inherent weaknesses of the 1997 ACR classification criteria (table 3) [63]. 2019 EULAR/ACR SLE criteria and 2012 SLICC criteria were evaluated by research fellows at the time of the enrollment (T0) and evaluated annually, or on additional visits, during a 3-years In 2012, the Systemic Lupus International Collaborating Clinics (SLICC) network presented a set of criteria based on almost 1400 patient scenarios, including a derivation and a validation of the new criteria as well as of the 1997 ACR classification. Een systematische beoordeling en meta-analyse. van Royen-Kerkhof2, J. Our objective was to compare both criteria in a cohort May 15, 2019 · Background To date there are no specific classification criteria for childhood-onset systemic lupus erythematosus (cSLE). Oct 22, 2023 · Systemic Lupus International Collaborating Clinics (SLICC) encompasses 11 Clinical and 6 Immunological criteria, The patient should satisfy at least FOUR of the criteria including one clinical criterion and one immunological criterion, Biopsy proven Nephritis compatible with SLE in the presence of ANA or Anti-dsDNA antibodies in the absence of other lupus features is regarded as sufficient for The Systemic Lupus International Collaborating Clinics (SLICC) group revised and validated the American College of Rheumatology (ACR) systemic lupus erythematosus (SLE) classification criteria in Jun 16, 2016 · The most recent criteria were published by the Systemic Lupus International Collaborating Clinics (SLICC) in 2012. 1%), SjD (8%), inflammatory arthritis (IA, 3. These criteria introduced a requirement for at least one clinical and one immunological criterion and two others from an expanded list of items (Table 5) compared with the ACR criteria (Table 4) [256]. The SLICC group validated the classification criteria in a new validation sample of 690 new expert-rated patient scenarios. Fritsch-Stork1,3. Feb 25, 2019 · To validate Systemic Lupus International Collaborating Clinics (SLICC)-12 and American College of Rheumatology (ACR)-97 classification criteria on a patient cohort from the University Hospital Center Zagreb. This retrospective study, conducted from 2014 To our knowledge, this is the largest cohort study of pediatric SLE to test the performances of all 3 classification criteria. Sep 11, 2019 · Neuropsychiatric Criteria Neuropsychiatric manifestations of SLE were added in the 2012 SLICC classification criteria; disease definitions were refined to include delirium, psychosis, or seizure in the 2019 EULAR/ACR recommendations, and were evaluated for their sensitivity. The 2012 Systemic Lupus International Collaborating Clinics (SLICC) classification criteria addressed many of these issues. The Systemic Lupus International Collaborating Clinics (SLICC) developed new SLE criteria to improve the American College Comprehensive diagnostic criteria for Systemic Lupus Erythematosus (SLE) based on the 2012 SLICC guidelines. Jacobs1, P. Hartman1, A. 2,3 Compared with the 1982 and 1997 ACR cri-teria, SLICC-12 contains additional clinical and immunological items and accepts cases with Results: The weighted SLICC criteria and the EULAR/ACR 2019 criteria had less sensitivity but better specificity compared to the list-based revised ACR 1997 and SLICC 2012 classification criteria. Sep 8, 2022 · Background and aims Several different versions of classification criteria, including the American College of Rheumatology (ACR)-1997, Systemic Lupus International Collaborating Clinics (SLICC)-2012 and European Alliance of Associations for Rheumatology (EULAR)/ACR-2019 classification criteria, have been launched in the past decades. Results Supplementary Figure 1. Systemic Lupus International Collaborating Clinics (SLICC) Criteria for SLE Clinical Criteria Acute cutaneous lupus Chronic cutaneous lupus Nonscarring alopecia Oral or nasal ulcers The SLICC criteria classified more African-American subjects by the leucopenia/lymphopenia criterion than did ACR criteria. 1 The 1997 ACR criteria (right) classify subjects with SLE if they Mar 17, 2017 · Objective SLE is traditionally classified using the American College of Rheumatology (ACR) criteria. Comparison of SLE classification criteria under 2012 SLICC and 1997 ACR criteria. Both the 1982/1997 ACR classification criteria and the 2012 SLICC criteria defined exclusion criteria for various items. <\/p>\n The SLICC criteria for SLE classification requires: 1) Fulfillment of at least four criteria, with at least one clinical criterion AND one immunologic criterion OR 2) Lupus nephritis as the sole clinical criterion in the presence of ANA or anti-dsDNA antibodies. Mucocutaneous and neuropsychiatric manifestations were added, as were hypocomplementemia and new anti-phospholipid antibody tests; and criteria definitions were refined. Mucocutaneous Criteria Dec 22, 2022 · Introduction: The American College of Rheumatology (ACR) 1997, Systemic Lupus International Collaborating Clinics (SLICC) 2012, and European League Against Rheumatism (EULAR)/ACR 2019 SLE criteria are often used to classify patients with adult-onset and childhood-onset systemic lupus erythematosus (SLE) in clinical practice because there are Overall, the 1997 ACR and the 2012 SLICC criteria are similar to classify SLE in an uncontrolled real-life scenario, although several new items contained in the 2012 SLICC criteria could represent a step forward for research purposes in selected clinical settings. The SLICC 2012 criteria yielded the best sensitivity, whereas the ACR 1997 criteria had the best specificity. SLICC is dedicated to generating new knowledge in the field of lupus, and translating these basic and clinical research discoveries into better health care practices and policies to help provide a healthier future for people diagnosed with lupus. 4%). 1Universitair Medisch One of the key elements that were changed for the EULAR/ACR criteria in comparison to the older sets of criteria is attribution. May 1, 2016 · The Systemic Lupus International Collaborating Clinics (SLICC) developed new SLE criteria to improve the American College of Rheumatology (ACR) criteria but the SLICC criteria have not been evaluated in patients with SCLE. Jan 1, 2018 · The importance of valid SLE classification criteria in the nephrology clinic recently gained attention by the increased weight that was attributed to renal lupus in the Systemic Lupus International Collaborating Clinics (SLICC) 2012 classification. 1007/978-981-15-8323-0_25 Approximately 50% of patients with subacute cutaneous lupus erythematosus (SCLE) meet criteria for systemic lupus erythematosus (SLE). Oct 1, 2022 · This year, the American College of Rheumatology (ACR) 1982 classification criteria for systemic lupus erythematosus (SLE) celebrate their 40th anniversary. The Systemic Lupus International Collaborating Clinics (SLICC) recently validated an alternative system. Third, due to the low incidence of SLE, clinicians must carefully balance considering SLE as a However, the extent to which patients satisfying MCTD criteria may also satisfy SLE criteria (or vice-versa) has not been reported since the introduction of the 2012 SLICC SLE criteria. Sensitivity, specificity, PPV, NPV of the 2019 EULAR/ACR SLE and 2012 SLICC criteria are reported in Table 2. 2, 3 Compared with the 1982 and 1997 ACR criteria, SLICC-12 contains additional clinical and immunological items and accepts cases with “renal Systemic lupus erythematosus (SLE) is an autoim-mune disease that afects multiple organ systems. Almoallim H, Cheikh M, editors. Gladman was a key facilitator in the development and validation of the SLICC/ACR Damage Index. Its course is typically recurrent, with periods of relative remission fol-lowed by flare-ups. Adjusting the thresholds of the EULAR/ACR- 2019 criteria from 10 to 12, the specificity and accuracy significantly increased. The Systemic Lupus International Collaborating Clinics (SLICC) group revised and validated the American College of Rheumatology (ACR) systemic lupus erythematosus (SLE) classification criteria in . Objective To develop new classification criteria for systemic lupus erythematosus (SLE) jointly supported by the European League Against Rheumatism (EULAR) and the American College of Rheumatology (ACR). SLICC 2012 criteria performed better than EULAR/ACR 2019 criter … May 15, 2019 · Background To date there are no specific classification criteria for childhood-onset systemic lupus erythematosus (cSLE). The SLICC criteria are validated criteria for making the diagnosis of lupus. Hematological involvement is scored differently by these classifications. Jul 29, 2016 · To address these and some other issues, the SLICC group devised alternative classification criteria for lupus [258]. A group of rheumatologists came up with SLICC criteria in 2012 to improve clinical relevance, and to incorporate the new knowledge of SLE immunology. Presentatie op het “ Autoimmuniteit” congres in Lissabon, Portugal, mei 2018 Auteurs: E. Author manuscript; available in PMC 2013 August 01. Of note, we also compared the median time interval between the appearance of the earliest item and fulfilment of the three sets of criteria, suggesting the SLICC- 2012 and EULAR/ACR- 2019 could achieve earlier diagnosis. doi: 10. There were no statistically significant differences between any pair of rules with respect to overall agreement with the physician diagnosis. Jun 29, 2020 · The EULAR/American College of Rheumatology 2019 classification criteria for systemic lupus erythematosus did not perform significantly better than the ACR 1997 and SLICC 2012 criteria, according Oct 12, 2022 · Conclusions: SLICC-2012 and EULAR/ACR-2019 have better diagnostic ability than the ACR-1997, and the sensitivity of the former two criteria is also higher than that of the latter; Moreover, the SLICC-2012 and EULAR/ACR-2019 for patients in the early stages of disease performed equally excellent. A service of the National Library of Medicine, National Institutes of Health. To date, there are no classification criteria specific for children with SLE. Because of the unknown diagnostic performance among patients from nephrology clinics, we aimed to Purpose of review: To compare the recently published European League Against Rheumatism (EULAR)/ American College of Rheumatology (ACR) classification criteria for SLE with the Systemic Lupus International Collaborating Centers (SLICC) criteria and the earlier ACR criteria, focusing on their key concepts. The Systemic Lupus Collaborating Clinics (SLICC) revised and validated the American College of Rheumatology (ACR) SLE classification criteria in order to improve clinical relevance, meet stringent methodology requirements and incorporate new This systemic lupus diagnostic criteria SLICC calculator helps the classification and diagnosis of SLE based on clinical and immunological criteria. Methods Medical records of subjects in the May 2, 2019 · In 2012, the Systemic Lupus International Collaborating Clinics (SLICC) network presented a set of criteria based on almost 1400 patient scenarios, including a derivation and a validation of the new criteria as well as of the 1997 ACR classification. 5% vs 81. f Petri et al. SLICC criteria (left) classify subjects with SLE if they meet ≥4 criteria, including at least one clinical and one immunologic criterion, or if they exhibit biopsy-proven lupus nephritis with positive ANA or anti-dsDNA. As an example, one of the major limitations of the 1997 ACR criteria is that patients with biopsy-confirmed lupus nephritis could still fail to fulfill criteria. In 1998, the SLICC group established a longitudinal cohort of newly diagnosed patients with lupus (SLICC Inception Cohort) to better understand risk Jan 24, 2025 · Key Publications Damage Index SLE Criteria Inception Cohort Prevalent Cohort All Publications In 2012, the Systemic Lupus International Collaborating Clinics (SLICC) presented a new classification for systemic lupus erythematosus (SLE). May 21, 2025 · Methods We included all consecutive consenting patients with ANA positive ≥ 1:80, new symptoms of ≤ 1 year, and SLE treatment naïve who had been referred to a specialist lupus clinic from primary care. Singapore: Springer; 2021. Sep 1, 2020 · This SLICC criteria calculator helps diagnose Systemic Lupus Erythematosus based on lupus nephritis, clinical and immunological symptoms. The current study aimed to investigate the performance of The Systemic Lupus Collaborating Clinics (SLICC) revised and validated the American College of Rheumatology (ACR) SLE classification criteria in order to improve clinical relevance, meet stringent methodology requirements and incorporate new knowledge In this first independent evaluation of a limited number of cases, we found comparable results with respect to diagnostic sensitivity, specificity and accuracy regarding the SLICC-12 and the proposed EULAR/ACR classification criteria. This study aims to compare the performance among the American College of Rheumatology (ACR) 1997, the Systemic Lupus International Collaborating Clinics criteria (SLICC) and the new European League Against Rheumatism (EULAR)/ACR criteria, in a cSLE cohort. Results Jun 10, 2021 · The EULAR/ACR classification criteria project set out with the goal of preserving the excellent specificity of the ACR 1982 and 1997 classification criteria, while reaching better sensitivity, if possible, in the range of the Systemic Lupus International Collaborating Centers’ (SLICC) 2012 criteria. SLE is traditionally classified using the American College of Rheumatology (ACR) criteria. SLICC CLASSIFICATION CRITERIA FOR SLE Amith Balachandran, Department of Anaesthesia, CMC Vellore, and Ashish Jacob Mathew, Assistant Professor, Department of Rheumatology, CMC, Vellore. It should be noted that the new SLICC criteria are likewise for the purpose of classification and cannot replace the clinical diagnosis; and it is important to stress that disease management When making the diagnosis of SLE, clinicians refer to the Systemic Lupus International Collaborating Clinics (SLICC) classification criteria revised in 2012 (Table 1) 8 . The 2012 Systemic Lupus Collaborating Clinics (SLICC) Criteria for Systemic Lupus Erythematosus diagnoses systemic lupus erythematosus (SLE). The 2012 SLE SLICC criteria [4]. Immune processes that contribute to lupus susceptibility and lupus activity have become increasingly well-defined. Methods This international initiative had four phases. 4%), whereas 2019 EULAR/ACR criteria exhibited greater specificity compared to 2012 SLICC (86. This process took well over a decade from its conception to publication. ConclusionThe 2019 EULAR/ACR criteria classified patients with higher sensitivity at diagnosis and at the first-year follow-up. This study examined large cohorts of subjects with SLE and incomplete lupus erythematosus (ILE) to compare the impact of ACR and SLICC criteria. Download scientific diagram | SLICC Classification Criteria for Systemic Lupus Erythematosus from publication: Gastrointestinal and neurological manifestations in systemic lupus erythematosu Approximately 50% of patients with subacute cutaneous lupus erythematosus (SCLE) meet criteria for systemic lupus erythematosus (SLE). Overall, the 1997 ACR and the 2012 SLICC criteria are similar to classify SLE in an uncontrolled real-life scenario, although several new items contained in the 2012 SLICC criteria could represent a step forward for research purposes in selected clinical settings. In 2012, the Systemic Lupus International Collaborating Clinics (SLICC) network presented a new set of criteria (SLICC-12) to classify systemic lupus erythematosus (SLE). NCBI Bookshelf. The 2012 SLICC criteria could represent a step forward for research purposes in selected clinical settings of SLE Sep 19, 2022 · EULAR/ACR criteria was better at correctly identifying lupus cases compared to the ACR 1997 criteria and comparable in performance to the SLICC criteria. 7%, respectively). <\/p Jun 1, 2021 · The Performances of the ACR 1997, SLICC 2012, and EULAR/ACR 2019 Classification Criteria in Pediatric Systemic Lupus Erythematosus Abstract Background and aims Several different versions of classification criteria, including the American College of Rheumatology (ACR)-1997, Systemic Lupus International Collaborating Clinics (SLICC)-2012 and European Alliance of Associations for Rheumatology (EULAR)/ACR-2019 classification criteria, have been launched in the past decades. A positive ANA test is obligatory The aims of this study were to determine damage index in systemic lupus erythematosus (SLE) patients based on Systemic Lupus International Collaborating Clinics/American College of Rheumatology (SLICC/ACR) Damage Index (SDI) and to determine the May 13, 2020 · One of the key elements that were changed for the EULAR/ACR criteria in comparison to the older sets of criteria is attribution. (1) Evaluation of antinuclear antibody (ANA) as an entry criterion through systematic review and meta-regression of the literature and Conclusion. pylkd 8lu dnox n1e43 pc3o0 t2oamv 17r6p 4h va nffyji