Skeletal fluorosis in young girl india. Dec 1, 2017 · Fluorosis, caused by ingestion of excess fluoride, is endemic in at least 25 countries across the globe, China and India being the worst affected among them. We assess the prevalence and pathogenic stage of skeletal fluorosis among children and adolescents residing in a severe coal-burning endemic fluorosis area of southwest China. 04. This predominant selection of rural areas was because most of the Millions of people worldwide are found suffering from fluorosis. The percentage shown with the number total number of people of prevalence affected people surveyed. A number of genetic epidemiological studies carried out by investigators have shown the evidence for association between Dec 13, 2024 · In India, fluoride poisoning or fluorosis in humans and animals is a result of repeated long-term exposure to fluoride through drinking fluoridated water and/or industrial fluoride pollution. e. Choubisa. Abstract Fluorosis occurs due to excessive fluorine entry into the body. 5 mg/l), and about bout 62 million people in India suffer from dental, skeletal and non-skeletal fluorosis. , Skeletal Fluorosis. Our Beginning Young Girls India, Inc came into being when the founder Sarah Murphy Travis travelled to India in the Spring of 2019. Hence, the objectives of present study are to assess the prevalence of skeletal fluorosis, to evaluate the hematological, biochemical and radiological changes in skeletal and non-skeletal fluorosis in endemic fluoridated areas and to evaluate the morphology changes in red blood cells wall. Skeletal fluorosis is a bone disease caused by excessive accumulation of fluoride leading to weakened bones. This prompted us to take up the study to evaluate the toxicity of fluoride in drinking water on the teeth (dental fluorosis) and on the bones (skeletal fluorosis) in school children in endemic fluoride areas in the YSR district as early fluorosis can be easily observed in children’s teeth and bones. Dental fluorosis is highly prevalent in 24 countries of the world, including India. Young boys and girls are mostly affected by dental fluorosis, whereas adults are affected more by skeletal and non-skeletal fluo-rosis13. [3, 4] Nearly 6 million people in India are disabled because of fluorosis. Sarah decided to be Mar 23, 2020 · No specific treatments are available to date to treat skeletal fluorosis affectively; therefore, prevention is one of most safest and best approach to fight fluorosis. The clinical diagnosis of subjects showed 96. Teeth become weak, discolored and fall out at an early age (dental fluorosis) while various bones become porous, weak and deformed (skeletal fluorosis) and most people become hunchbacked and lame. Fluoride may cause a crippling Email: Abstract: Fluoride toxicity is a burgeoning problem in worldwide and also in Rajasthan, India. [3, 4] Caries preventive effect of fluoride at concentration of 1 ppm has been well documented [5, 6] but at the same time ill effects of chronic fluoride toxicity in the form of dental fluorosis and skeletal fluorosis is also a matter of concern. Dental Fluorosis in Domesticated Animals in and Around Umarda Village of Udaipur, Rajasthan, India Lalita Panchal1, Zulfiya Sheikh2* 1Research Scholar, Department of Zoology, Govt. Detailed scientific information on the non-skeletal, skeletal and dental fluorosis entities of the disease paved the way to develop diagnostic tests for fluorosis, and the disease is diagnosed at very early stages [12, 13]. The presented editorial focuses on how skeletal fluorosis is dangerous and how it can be prevented in the humans. 16% prevalence of skeletal Publications on Fluoride Toxicity & Fluorosis: On Human Subjects List of Publications Fluoride and Fluorosis Mitigation: Indian Contributions and its Impact, A. Out of 30 different areas, 25 places in rural areas and 5 places in urban areas were selected for this study. This predominant selection of rural areas was because most of the Aug 3, 2022 · Fluorine is regarded as an essential microelement that protects teeth against microbes and decay, especially in childhood. Objectives: To assess the prevalence of skeletal fluorosis in Bangarpet taluk of Kolar, to compare various epidemiological factors influencing the occurrence of skeletal fluorosis among the two groups with differential water fluoride levels, and to estimate fluoride High levels of fluoride in the drinking water, especially ground water, results in skeletal fluorosis which involves the bone and major joints. Key prevention methods include defluoridation of water, improving nutritional status, and promoting awareness and The effects range from mild dental fluorosis to crippling skeletal fluorosis as the level and period of exposure [1]. Mar 1, 2020 · PDF | On Mar 1, 2020, Lou Del Bello published Fluorosis: an ongoing challenge for India | Find, read and cite all the research you need on ResearchGate Skeletal fluorosis is a metabolic bone disease caused by accumulation of fluoride and is generally associated with chronic exposure to fluoride-contaminated groundwater, a phenomenon endemic to developing countries. Recent Findings Skeletal fluorosis, a major health issue that is endemic in some regions, affects millions of people worldwide. Meera Girls College, Udaipur- 13001, Rajasthan, India 2Lecturer, Department of Zoology, Govt. Conventional radiographs and more recently MRI are helpful in diagnosis of fluorosis which classically reveals a wide and intriguing spectrum of findings. This study was conducted to assess the prevalence of skeletal fluorosis to compare with dental fluorosis . A total of 1,616 students Oct 20, 2023 · Purpose of Review We performed a systematic review and meta-analysis on the relation between fluoride exposure and skeletal fluorosis (SF) using a novel statistical methodology for dose-response modeling. Therefore, diagnostic methods that can be easily performed even by primary Dental Fluorosis in Domesticated Animals in and Around Umarda Village of Udaipur, Rajasthan, India Lalita Panchal1, Zulfiya Sheikh2* 1Research Scholar, Department of Zoology, Govt. Anaemia in adolescent girls: An Intervention of diet editing and counselling Water contamination is one of the major effect on public health in India. Skeletal fluorosis in young man, India . We review the Feb 15, 2022 · In humans, basically three forms of fluorosis namely dental, skeletal and non-skeletal fluorosis have been recognised. Mar 1, 2020 · PDF | On Mar 1, 2020, Lou Del Bello published Fluorosis: an ongoing challenge for India | Find, read and cite all the research you need on ResearchGate Oct 28, 2020 · Excessive intake of fluorides can lead to the development of fluorosis, a serious public health issue in India. In this disease, people's teeth and bones are adversely affected. However, data regarding the dose-response relation between Materials and method: A descriptive cross-sectional survey was conducted on 653 fishermen from the Kutch District, Gujarat, India, from October 2014 to December 2014. B. To examine (a) prevalence of dental and skeletal fluorosis in adolescents from upper, middle, and lower socioeconomic strata (SES) and (b) May 2, 2024 · Department of Advanced Science and Technology, National Institute of Medical Science and Research, NIMS University Rajasthan, Jaipur, Rajasthan, India; Former Department of Zoology, Government Meera Girls College, MLS University, Udaipur, Rajasthan, India. 7 to 1. Actually, skeletal fluorosis is a bone disease caused by excessive accumulation of fluoride which weakens the bones. As of 2017, 62 million Indians are affected by dental fluorosis. It is an endemic problem as a result of long-term exposure to high amounts of fluoride. To tackle the problem, Government of India launched the National Programme for Prevention and Control of Fluorosis (NPPCF). The diagnosis of fluoride intoxication (fluorosis) in humans is made on the basis of history, clinical or pathognomonic signs and testing of biological samples. 9 ±8. A detailed fluorosis study was done in 63 habitations with >5. 25 However, there are no studies on the effect of VDR-FokI on skeletal fluorosis of the brick-tea type. A total of 1,616 Sep 21, 2015 · Exposure to a high amount of fluoride while the teeth are forming, can lead to dental fluorosis and skeletal fluorosis. Certain members of the public are at particularly high risk of harm. Hormo … Apr 19, 2022 · Discussion Many studies have been done to identify the prevalence of dental caries and fluorosis in different parts of India; however, limited data have been reported in the literature of the Rohtak district of Haryana. Chronic endemic fluorosis is prevalent in India and other Asian Millions of people worldwide are found suffering from fluorosis. Nava Thakuria reports. Fluoride pollution in water is a main difficult across the world, with health dangers such as dental and skeletal fluorosis. 2 In the US, data from a 1999–2004 national health and nutrition examination survey 3 and Objectives. It results in major health disorders like dental fluorosis, skeletal fluorosis and non-skeletal fluorosis. 1 In India, 60 million people are estimated to have health problems because of consumption of fluoride-contaminated water. Drinking water fluoride concentrations in different regions of the study area were determined. It may be serious problems in health of the adults and children. The study aims to assess the degree and severity of dental and skeletal fluorosis and examine the broader effects of fluorosis on human health and society in the Manbhum-Singhbhum Plateau region, India. Nonskeletal fluorosis is considered reversible if diagnosed early and treated promptly. Dental, skeletal and non-skeletal fluorosis is different types of fluorosis. The cross-sectional study was conducted at Vidharbha region of Maharashtra, India. 62%) and 1183/4839 (26. Among these young, nearly 20,000 are in Assam alone, and in Karbi Anglong, well known for its scenic beauty and thick forests, a tenth of the population is afflicted with dental or skeletal fluorosis. 49% prevalence of dental fluorosis, and 63. ’s). Treatment involves removing the source of fluoride and managing symptoms. Although there are national programs in place to raise awareness and curtail this disease condition, skeletal fluorosis continues to cause crippling deformities in areas where it continues to be endemic. 5 ppm fluoride. India lies in the geographic fluoride belt that extends from Turkey to China and Japan through Iraq, Iran, and Afghanistan. Meera Girls College, Udaipur- 313001, Rajasthan, India The review on fluorosis addresses the genesis of the disease, diagnostic protocols developed, mitigation and recovery through nutritional interventions. The latter is extremely painful and irreversible. The current epidemiological study focused on the prevalence and risk factors of fluorosis in the fluoride endemic village, Dongargaon, Maharashtra, India. In Nov 14, 2017 · A simple colour-changing test to detect fluoride in drinking water could help prevent skeletal fluorosis, the crippling bone disease, in developing countries like India, says a study. The effects range from mild dental fluorosis to crippling skeletal fluorosis as the level and period of exposure [1]. [3] The most seriously affected endemic skeletal fluorosis states in India are Andhra Pradesh, Punjab, Haryana, Rajasthan, Gujarat Fluorosis is controlled by the duration of fluoride exposure and calcium and Vitamin D nutrition status. Jan 9, 2007 · Of 62 million Indians suffering from fluorosis, more than six million are children and young people. Excessive intake has detrimental effects on skeletal tissue and other organs. In this study, we observed pathological lesions consistent with fluorosis on two human skeletons from the Ming Feb 26, 2025 · Background Fluorosis caused by excess intake of fluoride can affects various soft tissues of the body, such as the gastrointestinal tract, blood, brain tissues and thyroid gland apart from dental fluorosis and skeletal fluorosis. Out of these; 6 million are children below the age of 14 years [9]. Dec 1, 2016 · Out of a total 29 states in India, groundwater of 20 states is fluoride affected. Therefore, diagnostic methods that can be easily performed even by primary Dental fluorosis was highest in 13-15 years age group with boys more commonly affected than girls. Sizzling onion, potato, and chickpea preparations flavoured with turmeric, chilli, and fresh coriander are a common sight along the roads of the Indian capital Delhi, where small crowds gather at any time of the day for a The available data suggest that 15 States in India are endemic for fluorosis (fluoride level in drinking water >1. Fluorosis is a well-known endemic disease affecting the hard tissues of the human body like teeth and bone and soft tissues like the kidneys, gastrointestinal system, nervous system, etc. The Dean’s Community Fluorosis Index for the study area varies from 1. non-skeletal fluorosis. Of the 4,11,744 patients identified with the disorders of bone and mineral metabolism, 2,13,760 (52%) had nutritional bone disease, 1,77,200 (43%) had endemic skeletal fluorosis and 20,784 (5%) had metabolic bone disease and in 41 patients (0. We used a cross-sectional design. Dental fluorosis is being proven as a biomarker Jan 14, 2022 · In this communication, besides the status of chronic fluoride intoxication in the form of osteo-dental and non-skeletal fluorosis in buffaloes, determinations, bio-indicators and bio-markers of fluorosis and prevention and control of chronic fluoride poisoning in these animals are also considered and briefly and critically reviewed. General information regarding age, gender and adverse habits Objectives. J. e fractures. [1] Fluoride toxicity manifests with myriad rheumatological manifestations, ranging from early intermittent arthralgias to persistent inflammatory joint pain and later restrictive arthropathy. Dental, skeletal and non-skeletal are the major types of fluorosis affecting millions of people in these countries. Women may also face problems in delivery due to skeletal fluorosis. Although nutritional deficiencies and hot climates make populations in India and China more susceptible to fluoride toxicity than is generally the case in western countries, this fact does not remove the relevance of the Indian and Chinese Oct 5, 2015 · Catch them young: Treating children affected by fluorosis Why is fluorosis more toxic for children? What is the link between fluoride and calcium deficiency? These questions and more answered. by of fluorosis fluorosis Totally in was the 1702 respective calculated boys age between Besides dental and skeletal fluorosis, the ‘linked disorders’ cover a range of life-threatening diseases incapacitating the population in both rural and urban settings in the country. Background Andhra Pradesh (AP) is one of the states in India found to have districts with endemic fluoride and YSR Kadapa district is one among them. Jan 14, 2022 · In this communication, besides the status of chronic fluoride intoxication in the form of osteo-dental and non-skeletal fluorosis in buffaloes, determinations, bio-indicators and bio-markers of fluorosis and prevention and control of chronic fluoride poisoning in these animals are also considered and briefly and critically reviewed. Not only the pitted enamel seen in Dental Fluorosis aggravates dental damage but also a long- term intake of Fluoride may lead to a crippling disorder i. The purpose of this editorial is to provide scientific information and create awareness about this fluorosis disease among people living in fluoride endemic areas. Thus endemic skeletal fluorosis in India continues to be a national health problem and the drinking water remains the major source of intake of excess of fluoride. The objective of this study was to assess the impact of community defluoridation in preventing fluorosis in Kaiwara village. In advanced state, skeletal fluorosis causes varying degree of damage to the bones and joints depending on the fluoride concentration and its duration of exposure. Dental fluorosis is being proven as a biomarker for Fluorosis Fluorosis can happen if you ingest too much fluoride over a long period of time. The first ever report of endemic skeletal fluorosis and neurological manifestation was from Prakasam district in Andhra Pradesh in the year 1937. May 29, 2021 · However, in India, the maximum and outstanding research work on fluoride distribution in drinking groundwater and its chronic intoxication or endemic fluorosis has been done in the state of These animals develop a number of toxic efects on their teeth (dental fluorosis), bones (skeletal fluorosis) and soft organs (non-skeletal fluorosis) due to chronic industrial fluoride intoxication. 08 to 3. Skeletal fluorosis affects your bones and joints. 19%) the bone disease was rare, mixed or unidentified. Conclusion: Fluorosis incidence is directly related to fluoride intake through drinking water. Several young children in Jhabua suffer from skeletal fluorosis (Source: INREM Foundation) Fluorosis: an ongoing challenge for India High levels of fluoride from food and contaminated groundwater are putting many people in India at risk of fluorosis, an underappreciated and sometimes debilitating disease. The decision of the GOI to set up a Centre of Excellence for Fluorosis Research and address the various issues was a step in the right direction. 51%), respectively. About 62 million people, including 6 million children are at risk of fluorosis in India [2]. Of those 52 % had nutritional bone diseases, 43 % had endemic skeletal fluorosis and 5 % had metabolic bone diseases. Feb 26, 2025 · Background Fluorosis caused by excess intake of fluoride can affects various soft tissues of the body, such as the gastrointestinal tract, blood, brain tissues and thyroid gland apart from dental fluorosis and skeletal fluorosis. Whereas elevated water fluoride Nov 21, 2024 · Abstract Fluorosis, a debilitating disease, causes dental mottling and bone deformities among other adverse health effects. This community Nov 10, 2016 · Our previous study demonstrated ethnic differences in the prevalence of brick-tea type fluorosis and that the glutathione S-transferases rs1695 polymorphism may play an important role in the pathogenesis of brick-tea fluorosis. Nath, Vinod Prakash Sharma, Published by Springer. K. We review the various Oct 1, 2017 · Skeletal fluorosis is endemic in the sub-Himalayan belt in India. The current review lays emphasis on the skeletal fluorosis and its prevalence in recent years. Endemic skeletal fluorosis is prevalent in many countries including India. The overall prevalence of dental and skeletal fluorosis was found to be 5880/9242 (63. In advanced cases, skeletal fluorosis causes painful damage to bones and joints. High levels of fluoride from food and contaminated groundwater are putting many people in India at risk of fluorosis, an underappreciated and sometimes debilitating disease. However, the severity of skeletal fluorosis depends not only on the fluoride concentration and the duration and Sep 29, 2020 · The disease caused by excess exposure is known as Fluorosis and is mainly of two types- Dental Fluorosis and Skeletal Fluorosis. Focus on Dangerous Skeletal Fluorosis, how it can be Abstract Background Andhra Pradesh (AP) is one of the states in India found to have districts with endemic fluoride and YSR Kadapa district is one among them. According to a recent study undertaken in 24 villages of the taluk, about 90 per cent of the population had been affected by fluorosis. The histopathological appearance of such teeth shows areas of enamel porosity and hypomineralization, According to its severity, dental fluorosis can be classified as mild, moderate and severe. Symptoms of of and dental Telangana, expressed and skeletal South as percentage fluorosis India was prevalence were assessed villages in from area Figure 2. While traveling through urban India and getting to know the families along her way, she noticed there was a fundamental difference between the expected roles of the boys and the girls, and the value of their education was remarkably different. EPIDEMIOLOGY (INCIDENCE, PREVALENCE AND DISTRIBUTION) Endemic skeletal fluorosis is widely prevalent in India and is a major public health problem in nearly 25 countries in Asia and Africa. Fluorosis is a crippling disease caused by the consumption of water and food containing excessive levels of fluoride. It reveals the structural and functional damages caused to skeletal muscle and erythrocytes, leading to clinical manifestations in fluorosis. In the present study, 55 male flurotic patients (age 33. Total population of fluoride endemic 201 districts of India is 411 million (40% of Indian population) and more than 66 million people are estimated to be suffering from fluorosis including 6 million children below 14 years of age. In general, chronic fluoride intoxication or fluorosis is manifested as dental fluorosis with the appearance of yellowish to brownish striations or mottling of teeth, and/or skeletal fluorosis where osteosclerosis, ligamentous and tendinous calcification, and extreme bone deformity result [4-8]. Excess fluoride affects the bones and teeth, weakens and does not allow them to grow properly. Jun 1, 2022 · Skeletal fluorosis is a metabolic bone disease that results from the chronic ingestion of fluoride. Groundwater is considered as the major source of drinking water in most places on earth [10]. Clinical skeletal fluorosis was assessed using three diagnostic tests. Methods. Meera Girls College, Udaipur- 313001, Rajasthan, India Fluorosis occurs due to excessive fluorine entry into the body. A total of 1,616 Skeletal fluorosis is rarely considered in paleopathological analyses, but in areas with relatively high fluoride in the environment, it may be an important cause of bone hyperplasia. 2 In the US, data from a 1999–2004 national health and nutrition examination survey 3 and May 13, 2012 · In India and China, scientists have repeatedly found that skeletal fluorosis occurs in populations drinking water with just 0. DISCUSSION Skeletal fluorosis (SF) is endemic in India. Dental fluorosis causes tooth discoloration. Several clinical and experimental studies have reported that the F induces bone deformities in skeletal fluorosis but mechanism of action is still unknown. It can be confused with seronegative spondyloarthropathy or Rheumatoid arthritis in the young; and, in the elderly, Diffuse Idiopathic The review on fluorosis addresses the genesis of the disease, diagnostic protocols developed, mitigation and recovery through nutritional interventions. An Aug 21, 2017 · Skeletal fluorosis in India due to high natural occurring fluoride in ground water. It discusses the mechanisms, symptoms, risk factors, diagnosis, prevention strategies, and the national program for fluorosis control in India. Mar 20, 2020 · Skeletal Fluorosis is a chronic bone and joint disease caused by long term consumption of fluoride, effecting millions around the world. *Corresponding Author: Shanti Lal Choubisa Citation: Shanti L. Feb 24, 2009 · Endemic skeletal fluorosis is widely prevalent in India and is a major public health problem. In Dr Desai’s report, they have separately Skeletal and Non-skeletal Fluorosis, we have taken only Musculo-skeletal Disease or Musculo-Skeletal Fluorosis, and so we cannot compare these two studies for this purpose. Health Effects of Fluoride Fluoride is a highly toxic substance that can cause a range of adverse health effects. It can cause pain, stiffness and bone deformities. We review the To evaluate skeletal and non-skeletal fluorosis in patients living at endemic fluoridated areas and also the morphological changes in red blood cells (R. Susheela, Chapter 9, Page 97-105, In : Water and Sanitation in the New Millennium, 2017, Edited by K. May 19, 2012 · Treatment of fluorosis, which affects the young and the old alike, has posed a daunting task of the medical fraternity. The spec-trum of fluorosis related health hazard that leads to cur-rent status, health challenges and mitigation measures have been studied by many scientists12. Excessive fluoride accumulates in bones and causes the bones to weaken. A young villager afflicted with severe dental fluorosis due to drinking of fluoridated groundwater in the state of Rajasthan, India characterised with bilateral stratified deep brownish staining Dental fluorosis was highest in 13-15 years age group with boys more commonly affected than girls. 1) were Sep 27, 2017 · The contributions emerged have led to a third entity of the disease, i. (2024). C. Background: Skeletal fluorosis is a crippling disease resulting from excessive exposure to high fluoride from different sources. Jan 20, 2020 · Chronic ingestion of significantly high levels of fluoride (greater than 3 ppm), most commonly through community water supplies, can cause dental fluorosis and rarely skeletal fluorosis. However, the severity of skeletal fluorosis depends not only on the fluoride concentration and the duration and The document outlines fluorosis, a public health issue caused by excessive fluoride intake, leading to dental and skeletal disorders. Once skeletal fluorosis develops it lasts a lifetime and is not curable. Jul 1, 2024 · Skeletal fluorosis is a chronic metabolic bone osteopathy characterized by extensive bone fixation of fluoride. As the names suggest, Dental Fluorosis is when the tooth enamel is damaged and Skeletal Fluorosis is when the bones are affected. You can correct it with cosmetic treatment. A number of genetic epidemiological studies carried out by investigators have shown the evidence for association between Oct 19, 2009 · Objectives. 0 mg/L fluoride and 9242 individuals were examined. Intake of fluoride higher than the optimum level is associated with dental and skeletal fluorosis. r8dcls 1gt d6bixjx6 fvep5 ggxiq cbmr kpouqg pp mfd1 i5q8